Metabolic Perturbation and Potential Markers in Patients with Esophageal Cancer

Table 1

Patients’ characteristics in the study of esophageal cancer.

Characteristics	Patients supplying serum	P1	Patients supplying tissue	P2	Healthy control
Gender (n, male/female)	19/5	1.000	15/4	1.000	17/4
Age [mean (range)]	60.2 (48–86)	0.960	65.4 (44–87)	0.122	60.0 (45–86)
Weight [mean (range)]	61.6 (42–78)	0.597	62.4 (42–79)	0.895	62.8 (47–75)
Histology (n)
ESCC	22	—	17	—	—
Adenocarcinoma	2	—	2	—	—
Histologic grade (n)
I	6	—	2	—	—
II	8	—	10	—	—
III	10	—	7	—	—
Location (n)
Cervical	0	—	0	—	—
Upper thoracic	1	—	1	—	—
Middle thoracic	11	—	7	—	—
Lower thoracic/EGJ	12	—	11	—	—
Lymph node metastasis (n)
Yes	13	—	8	—	—
No	11	—	11	—	—
CT (n/n)	17/20	—	16/16	—	—
ALT [mean ± SD]	24.87 ± 35.99	—	17.63 ± 6.18	—	—
Creatinine^a [mean ± SD]	78.21 ± 24.34	—	79.79 ± 27.50	—	—

^aSerum creatinine; EGJ: esophagogastric junction; CT: computer tomography; ALT: alanine transaminase; SD: standard deviation; P₁: value of the EC patients supplying serum compared with the healthy control; P₂: value of the EC patients supplying tissue compared with the healthy control.