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Gastroenterology Research and Practice
Volume 2017, Article ID 6360319, 8 pages
https://doi.org/10.1155/2017/6360319
Research Article

Safety and Efficacy of Exclusive Enteral Nutrition for Percutaneously Undrainable Abdominal Abscesses in Crohn’s Disease

1Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine Zhejiang University, Hangzhou, China
2Inflammatory Bowel Disease Center, Sir Run Run Shaw Hospital, School of Medicine Zhejiang University, Hangzhou, China
3Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China

Correspondence should be addressed to Wei Zhou; moc.nuyila@narvlwzun

Received 16 June 2017; Revised 27 July 2017; Accepted 3 August 2017; Published 30 August 2017

Academic Editor: Fernando A. M. Herbella

Copyright © 2017 Yibin Zhu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. The percutaneously undrainable abdominal abscesses in Crohn’s disease (CD) are not uncommon. The treatment protocol is still under debate. This study was conducted to assess the safety and efficacy of exclusive enteral nutrition (EEN) for percutaneously undrainable abscesses in CD. Methods. A consecutive cohort of 83 CD patients with percutaneously undrainable abdominal abscesses between January 2011 and June 2015 was retrospectively analyzed. They were divided into the EEN group and the non-EEN group. Results. The cumulative surgical rate was significantly lower in the EEN group than in the non-EEN group (). Fifteen percent patients treated with EEN avoided surgery. EEN () was associated with a decreased need for surgery. Previous abdominal surgery () and abscess diameter > 3 cm () were associated with an increased need for operation. EEN increased the albumin level, while decreased ESR and CRP significantly for patients requiring surgery. The risk of postoperative intra-abdominal septic complications () was significantly lower in the EEN group compared with the non-EEN group. Conclusions. EEN is feasible in CD patients presenting with percutaneously undrainable abdominal abscesses. It is associated with a reduction in surgical rate, optimized preoperative condition, and improved postoperative outcomes in these specific groups of patients.