Tumor Budding, uPA, and PAI-1 in Colorectal Cancer: Update of a Prospective Study

Figure 1

Test set: cancer specific survival of (a) uPA, (b) PAI-1, (c) tumor budding, and (d) a combination of tumor budding and PAI-1 (no or one positive versus double positive). Cut-offs: uPA ≥ 4.0 ng/mg protein; PAI-1 ≥ 40 ng/mg protein; tumor budding ≥ 30 buds/20-fold magnification.

(a)

(b)

(c)

(d)