TY - JOUR A2 - M'Koma, Amosy AU - Laffolie, Jan de AU - Laass, Martin W. AU - Scholz, Dietmar AU - Zimmer, Klaus-Peter AU - Buderus, Stephan AU - CEDATA-GPGE Study Group, PY - 2017 DA - 2017/12/05 TI - Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE® SP - 8424628 VL - 2017 AB - Aim. To determine the prevalence of anemia and its association with disease severity in children and adolescents with IBD. Methods. CEDATA-GPGE is a registry for pediatric patients with IBD in Germany and Austria from 90 specialized centers. As markers of disease severity, analysis included patient self-assessment on a Likert scale (1–5; 1 = very good) and physicians’ general assessment (0 = no activity to 4 = severe disease) and the disease indices. Anemia was defined as hemoglobin concentration below the 3rd percentile. Results. Prevalence of anemia was 65.2% in CD and 60.2% in UC. Anemic CD and UC patients showed significantly worse self-assessment than patients without anemia (average ± standard deviation; CD: 3.0 ± 0.9 versus 2.5 ± 0.9, p<0.0001; UC: 2.9 ± 0.9 versus 2.3 ± 0.9, p<0.0001). Accordingly, physicians’ general assessment (PGA) was significantly worse in anemic than in nonanemic patients in CD (p<0.0001) and UC (p<0.0001). PCDAI in anemic CD, p<0.0001, and PUCAI in anemic UC patients, p<0.0001, were significantly higher than in nonanemic patients. 40.0% of anemic CD and 47.8% of anemic UC patients received iron during follow-up. Conclusion. Almost 2/3 of pediatric IBD patients are anemic. Patients’ self-assessment and disease severity as determined by PGA and activity indices are worse in anemic patients. Contrastingly, only a minority received iron therapy. SN - 1687-6121 UR - https://doi.org/10.1155/2017/8424628 DO - 10.1155/2017/8424628 JF - Gastroenterology Research and Practice PB - Hindawi KW - ER -