Risk Factors Associated with the Occurrence of Autoimmune Diseases in Adult Coeliac Patients

Table 3

Risk factors for the association of autoimmune diseases (AD) in coeliac disease (CD) patients by logistic regression analysis in the whole group of included patients and in gender-age-matched patients.

	All included patients (); OR (95% CI)	Gender-age matched patients (); OR (95% CI)
Age at CD diagnosis
<40	1.0	—
≥40	1.2 (0.7–2.1)
Gender
Male	1.0	—
Female	0.65 (0.3–1.3)
Overweight (BMI ≥ 25 kg/m^2)
No	1.0
Yes	2 (1.1–3.8)	8.4 (2.9–24.8)
Gastrointestinal symptoms leading to CD diagnosis
No	1.0
Yes	1.2 (0.6–2.3)	0.6 (0.2–1.6)
Severe histological damage (Marsh 3C)
No	1.0
Yes	0.95 (0.6–1.7)	0.96 (0.4–2.15)
Family history of AD
No	1.0
Yes	3.7 (1.9–7)	6.9 (2.2–21.7)
Duration of symptoms ≥ 10 years before CD diagnosis
No	1.0
Yes	2.1 (1.1–3.7)	19.6 (5.3–73.1)