Comprehensive Complication Index Predicts Cancer-Specific Survival of Patients with Postoperative Complications after Curative Resection of Gastric Cancer

Table 1

Clinicopathological characteristics of patients undergoing radical gastrectomy.

	Total,	No complication,	Comprehensive complication index		(CCI < 26.2 vs. CCI ≥ 26.2)	Clavien-Dindo grade		(I–II vs. ≥IIIa)
			CCI < 26.2,	CCI ≥ 26.2,		I–II,	≥IIIa,
Age ± SD	59.54 ± 11.24	58.98 ± 11.20	61.66 ± 10.72	64.99 ± 10.54	<0.001	62.04 ± 10.85	65.45 ± 10.80	<0.001
Gender					0.458			0.481
Male	4028	3433	376	219		448	147
Female	1299	1127	114	58		134	38
Charlson index					0.068			0.004
0–2	5252	4507	480	265		571	174
≥3	75	53	10	12		11	11
ASA classification					0.001			<0.001
1–2	5059	4362	458	239		541	156
≥3	268	198	32	38		41	29
Neoadjuvant chemotherapy					0.564			0.926
No	5228	4481	476	271		567	180
Yes	99	79	14	6		15	5
Tumor diameter ± SD	51.60 ± 27.99	51.09 ± 27.72	55.08 ± 29.41	53.84 ± 29.28	0.576	54.37 ± 28.65	55.47 ± 31.52	0.656
TNM stage					0.924			0.987
I	1226	1068	102	56		120	38
II	986	863	80	43		94	29
III	3115	2629	308	178		368	118
Gastrectomy					0.073			0.188
Open	2719	2326	263	130		306	87
Laparoscopic	2608	2234	227	147		276	98
Extent of resection					0.705			0.276
Total	2945	2494	289	162		336	115
Distal	2249	1958	187	104		229	62
Proximal	133	108	14	11		17	8
Operative time ± SD	221.45 ± 71.72	218.93 ± 69.97	236.88 ± 84.93	235.02 ± 86.92	0.778	237.27 ± 85.49	232.93 ± 86.17	0.557
Blood loss ± SD	152.13 ± 274.15	139.86 ± 173.48	188.16 ± 281.02	286.57 ± 875.02	0.077	190.89 ± 272.76	326.75 ± 1055.49	0.092
Adjuvant chemotherapy					0.004			<0.001
No	3226	2655	348	223		413	158
Yes	2101	1905	142	54		169	27
Surgical period					0.013			0.317
1996–2005	1473	1299	125	49		137	37
2006–2014	3854	3261	365	228		445	148