Gastrointestinal Symptoms in Marfan Syndrome and Hypermobile Ehlers-Danlos Syndrome

Table 1

Gastrointestinal symptoms in MS/hEDS patients compared with controls.

	Controls	MS/hEDS patients	value (Fisher’s exact test)
Number	90	90
M : F	18 : 72	18 : 72
Symptoms
Abdominal pain	25	55	<0.0001
Diarrhoea	8	30	<0.0001
Constipation	15	49	<0.0001
Medicines
Antisecretory/antacids	17	48	<0.0001
Laxatives	13	46	<0.0001
Oesophageal disorders
Functional chest pain	1	6	0.1177
Functional heartburn	11	30	0.0012
Globus	1	3	0.6208
Functional dysphagia	3	13	0.016
Gastroduodenal disorders
Functional dyspepsia	7	25	0.0007
Belching disorders	4	10	0.016
Nausea and vomiting disorders	1	4	0.3680
Rumination syndrome	1	3	0.6208
Bowel disorders
Irritable bowel syndrome	6	21	0.0029
Functional constipation	11	32	0.0004
Functional diarrhoea	5	19	0.0036
Functional abdominal bloating/distension	6	23	0.0009
Unspecified functional bowel disorder	22	50	<0.0001
Centrally mediated abdominal pain syndrome	3	9	0.1324
Functional biliary pain	1	1	1
Anorectal disorders
Faecal incontinence	1	2	1
Functional anorectal pain	2	4	0.6822

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