Research Article

Gastrointestinal Symptoms in Marfan Syndrome and Hypermobile Ehlers-Danlos Syndrome

Table 3

Gastrointestinal symptoms in hEDS patients compared with controls.

ControlhEDS value (Fisher’s exact test)

Number4545
M : F6 : 396 : 39
Symptoms
 Abdominal pain1231<0.0001
 Diarrhoea421<0.0001
 Constipation733<0.0001
Medicines
 Antisecretory/antacids837<0.0001
 Laxatives734<0.0001
Oesophageal disorders
 Functional chest pain140.3607
 Functional heartburn6210.0011
 Globus121
 Functional dysphagia290.01
Gastroduodenal disorders
 Functional dyspepsia4170.0291
 Belching disorders270.2663
 Nausea and vomiting disorders130.6164
 Rumination syndrome120.6164
Bowel disorders
 Irritable bowel syndrome3150.0014
 Functional constipation6230.0002
 Functional diarrhoea3120.0014
 Functional abdominal bloating/distension3140.0059
 Unspecified functional bowel disorder1227<0.0001
Centrally mediated abdominal pain syndrome270.2663
Functional biliary pain111
Anorectal disorders
 Faecal incontinence111
 Functional anorectal pain120.6164

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