Research Article
Gastrointestinal Symptoms in Marfan Syndrome and Hypermobile Ehlers-Danlos Syndrome
Table 3
Gastrointestinal symptoms in hEDS patients compared with controls.
| | Control | hEDS | value (Fisher’s exact test) |
| Number | 45 | 45 | | M : F | 6 : 39 | 6 : 39 | | Symptoms | | | | Abdominal pain | 12 | 31 | <0.0001 | Diarrhoea | 4 | 21 | <0.0001 | Constipation | 7 | 33 | <0.0001 | Medicines | | | | Antisecretory/antacids | 8 | 37 | <0.0001 | Laxatives | 7 | 34 | <0.0001 | Oesophageal disorders | | | | Functional chest pain | 1 | 4 | 0.3607 | Functional heartburn | 6 | 21 | 0.0011 | Globus | 1 | 2 | 1 | Functional dysphagia | 2 | 9 | 0.01∗ | Gastroduodenal disorders | | | | Functional dyspepsia | 4 | 17 | 0.0291 | Belching disorders | 2 | 7 | 0.2663 | Nausea and vomiting disorders | 1 | 3 | 0.6164 | Rumination syndrome | 1 | 2 | 0.6164 | Bowel disorders | | | | Irritable bowel syndrome | 3 | 15 | 0.0014 | Functional constipation | 6 | 23 | 0.0002 | Functional diarrhoea | 3 | 12 | 0.0014 | Functional abdominal bloating/distension | 3 | 14 | 0.0059 | Unspecified functional bowel disorder | 12 | 27 | <0.0001 | Centrally mediated abdominal pain syndrome | 2 | 7 | 0.2663 | Functional biliary pain | 1 | 1 | 1 | Anorectal disorders | | | | Faecal incontinence | 1 | 1 | 1 | Functional anorectal pain | 1 | 2 | 0.6164 |
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