Differential Effects of Three Techniques for Hepatic Vascular Exclusion during Resection for Liver Cirrhosis on Hepatic Ischemia-Reperfusion Injury in Rats

Figure 7

Effects of different techniques for hepatic vascular exclusion during resection on Bcl-2, caspase-3, and HMOX1 expression after hepatic I/R in rats. (a) Bcl-2 protein expression in the PR, HH, and WH groups. Bcl-2 protein levels were significantly lower in the PR group than in the HH and WH groups (); (b) caspase-3 protein expression in the PR, HH, and WH groups. Caspase-3 protein levels were significantly higher in the PR group than in the HH and WH groups (). (c) HMOX1 mRNA expression was determined by real-time qRT-PCR as described in the Materials and Methods. HMOX1 gene expression was significantly higher in the HH and WH groups compared with the PR group and reached a peak value at 6 h after reperfusion ().

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