Review Article
The Value of Fecal Microbiota Transplantation in the Treatment of Ulcerative Colitis Patients: A Systematic Review and Meta-Analysis
Table 3
Subgroup analysis for FMT in UC patients (
).
| | Subgroups | Number of studies (n) | No. of enrolled patients | Remission rate (, %) | The value of | 95% confidence interval | Tests of homogeneity | | I2 |
| | Route of administration | | Enema | 4 | 135 | 33.37 ± 3.93 | | 0.25–0.41 | 0.35 | 8.4% | | Colonoscopy | 4 | 88 | 25.74 ± 11.00 | 0.19–0.44 | 0.09 | 58.3% | | Other | 2 | 34 | 15.98 ± 5.45 | 0.02–0.25 | 0.45 | 0.0% | | Donor relationship | | Related | 5 | 131 | 27.79 ± 8.63 | | 0.23–0.42 | 0.23 | 31.1% | | Unrelated | 2 | 51 | 36.95 ± 6.95 | 0.27–0.54 | 0.40 | 0.0% | | Unclear | 3 | 75 | 18.51 ± 4.24 | 0.10–0.27 | 0.35 | 5.5% | | Bacterial fluid status | | Fresh | 6 | 133 | 25.30 ± 7.55 | | NA | NA | NA | | Frozen | 1 | 41 | 43.9 | NA | NA | NA | | Unclear | 3 | 83 | 24.23 ± 3.5 | NA | NA | NA |
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Note: 95% CI: 95% confidence interval; NA: not available. Others: nasogastric tube insertion, gastroscopy, nasojejunal tube insertion, esophagogastroduodenoscopy; means pairwise comparison of subgroup. |
