Clinical Overview of GIST and Its Latest Management by Endoscopic Resection in Upper GI: A Literature Review

Table 2

Relevant outcomes of the endoscopic full-thickness resection and endoscopic-laparoscopic cooperative procedure for gastrointestinal subepithelial tumors.

Study	, GIST^1	Method	Mean tumor size (mm)	Mean procedure time (min)	Complete resection rate (%)	Complication (%)	Mean follow-up (mo), recurrence
Zhou et al. [44] (2011)	26, 16	EFTR	28.0	105.0	100	0	8.0, 0
Feng et al. [45] (2014)	48, 43	EFTR	15.9	59.7	100	1.0	6.0–24 (range), 0
Kappelle et al. [48] (2017)	13, 2	EFTR^2	11.0	—	84.6	38.5	3.0–6.0 (range), 0
Ye et al. [46] (2014)	51, 30	EFTR	24.0	52.0	98.0	0	22.4, 0
Hiki et al. [49] (2008)	7, 7	LECS	46.0	169.0	100	0	—
Namikawa and Hanazaki [50] (2015)	8, 8	LECS	31.0	213.0	100	0	—
Mitsui et al. [52] (2011)	6, 5	NEWS	34.8	273.5	100	0	8, 0
Goto et al. [53] (2016)	20, —^3	NEWS	—^3	213.5	100	5.0	10.1, 0
Nabeshima et al. [54] (2015)	2, 2	CLEAN-NET	37.5	165.0^4	100	0	—
Hajer et al. [56] (2018)	10, 4	NEWS CLEAN-NET	32.7	99	100	20	—
	2, 2		37.5	150	100	0

¹Total number of pathologically diagnosed GIST. ²EFTR using a new flat-based over-the-scope clip. ³Data unavailable due to limited access. ⁴One case underwent CLEAN-NET and cholecystectomy procedure. EFTR = endoscopic full-thickness resection; LECS = laparoscopic endoscopic cooperative surgery; NEWS = nonexposed endoscopic wall-inversion surgery; CLEAN-NET = endoscopic approaches to neoplasia with nonexposed technique.