Altered Intestinal Microbiota with Increased Abundance of Prevotella Is Associated with High Risk of Diarrhea-Predominant Irritable Bowel Syndrome

Figure 3

Relationship between AWR scores and histology in PI-IBS and control mice. (a) AWR scores to CRD. AWR scores at distention pressures of 40, 60, and 80 mmHg were significantly higher in PI-IBS mice than in control mice. (b) Hematoxylin and eosin (H&E) staining: representative sections of jejunum, ileum, and colon from PI-IBS or control mice (original magnification ×200). No evidence of inflammation, including neutrophil infiltration in the lamina propria or edema in interstitial tissues, was seen with PI-IBS mice compared with control mice. versus control.

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