A Retrospective Study Analyzing the Appropriateness of Initial Treatment of Clostridium difficile in Patients with Active Malignancy

Table 3

Outcomes in all treatment groups.

	Total ()	Metronidazole ()	Vancomycin ()	Combination ()	value
Length of stay, days (median)	9	9	9	10	0.89
Length of stay, days (mean)	14 ± 13	14 ± 14	14 ± 14	13 ± 10	0.16
Length of stay, days (range)	0 to 70	1 to 59	0 to 79	1 to 50
In-hospital all-cause mortality (%)	20 (10.2)	4 (11.8)	7 (6.7)	9 (15.3)	0.17
90-day all-cause mortality (%)	50 (25.4)	10 (29.4)	22 (21.2)	18 (30.5)	0.33
90-day recurrence rate (%)	39 (19.8)	8 (23.5)	24 (23.1)	7 (11.9)	0.18

There was no difference in hospital length of stay. In-hospital all-cause mortality and 90-day all-cause mortality were higher in the combination group, but not found to be statistically significant in-between all treatment groups. 90-day recurrence rate was lower in the combination group compared to the vancomycin or metronidazole groups ().