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Gastroenterology Research and Practice
Volume 2018, Article ID 8040262, 6 pages
https://doi.org/10.1155/2018/8040262
Research Article

Association between Helicobacter pylori Infection and Nonalcoholic Fatty Liver Disease: A Single-Center Clinical Study

1Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China
2Teaching and Research Section of Internal Medicine, College of Clinical Medicine, Xi’an Medical University, Xi’an, Shannxi, China
3Enshi Prefecture Center for Disease Control and Prevention, Enshi, China

Correspondence should be addressed to Shiyun Tan; nc.moc.liamdem@nuyihsnat

Received 2 September 2017; Revised 11 November 2017; Accepted 23 November 2017; Published 21 January 2018

Academic Editor: Francesco Selvaggi

Copyright © 2018 Ou Cai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To investigate the association between Helicobacter pylori (H. pylori) infection and nonalcoholic fatty liver disease (NAFLD). Methods. Data from 2051 participants who underwent 13C urea breath test and abdominal ultrasound examinations was collected. Participants were allocated to NAFLD risk group and NAFLD nonrisk group based on definite risk factors for NAFLD. The relationship between H. pylori infection and NAFLD was analyzed. Results. No significant difference was found between rates of H. pylori infection and NAFLD using the chi-square test () or regression analysis (). There was no significant difference between rates of H. pylori infection with and without NAFLD () in the NAFLD risk group or in the NAFLD nonrisk group (). There was no significant difference between rates of H. pylori infection in men () and in women () or in participants aged 18–40 years (), 41–65 years (), and ≥66 years () with and without NAFLD in the NAFLD risk group or between the same sex or age groups (, , , , and , resp.) in the NAFLD nonrisk group. Conclusions. H. pylori infection does not appear to increase the NAFLD prevalence rate or to be associated with, or a risk factor for, NAFLD.