Changes in Hepatic Blood Flow and Liver Function during Closed Abdominal Hyperthermic Intraperitoneal Chemotherapy following Cytoreduction Surgery
Table 2
Time course of biological data.
Time
Preoperative
ICU arrival
24 hours postoperative
48 hours postoperative
72 hours postoperative
value
ASAT (UI/l)
22 (19–29)
147 (75–299)
153 (62–353)
142 (56–180)
94 (51–130)
<0.001
ALAT (UI/l)
19 (13–25)
94 (26–193)
117 (28–281)
105 (42–193)
89 (41–172)
<0.001
Serum lactate (mmol/l)
0.9 (0.7–1.2)
1.7 (1.3–3.5)
1.4 (1.2–2.3)
0.7 (0.5–1.7)
1.1 (0.7–1.2)
0.013
Serum albumin (g/l)
33 (26–36)
23 (19–27)
21 (17–24)
22 (21–24)
22 (20–24)
0.031
Serum creatinine (μmol/l)
58 (55–79)
53 (44–70)
59 (50–78)
58 (48–74)
58 (52–65)
0.032
Data are expressed as median (quartile 25–quartile 75). value results from a Friedman’s two-way analysis of variance by rank. indicates a significantly different value compared to baseline with the Wilcoxon signed-rank test. ICU: Intensive Care Unit; ASAT: aspartate aminotransferase; ALAT: alanine aminotransferase.
