Research Article
Pure Well-Differentiated Adenocarcinoma Is a Safe Factor for Lymph Node Metastasis in T1 and T2 Colorectal Cancer: A Pilot Study
Table 4
The difference in various clinicopathological factors between cases with and without PWDA among T1 colorectal cancers.
| | PWDA | Non-PWDA | value |
| | Case number | 73 | 129 | | | Age, years; mean (range) | 65.7 ± 10.4 (32–84) | 66.0 ± 9.7 (24–88) | 0.849 | | Sex (male/female) %, (n) | 57.5 (42)/42.5 (31) | 58.1 (75)/41.9 (54) | 0.933 | | Tumor size, mm; mean (range) | 20.7 ± 11.9 (5–56) | 22.3 ± 12.6 (5–80) | 0.384 | | Location (colon/rectum) %, (n) | 71.2 (52)/28.8 (21) | 56.7 (73)/43.3 (56) | 0.039 | | Morphology (polypoid/nonpolypoid) %, (n) | 54.8 (40)/45.2 (33) | 65.1 (84)/34.9 (45) | 0.147 | | SM invasion (T1a/T1b) %, (n) | 27.4 (20)/72.6 (53) | 7.8 (10)/92.2 (119) | <0.001 | | SM invasion distance, μm; mean (range) | 2317 ± 1953 (50–10,000) | 3730 ± 2722 (100–14,000) | <0.001 | | Lymphatic invasion %, (n) | 24.7 (18) | 38.8 (50) | 0.041 | | Venous invasion %, (n) | 21.9 (16) | 25.6 (33) | 0.559 | | Budding grade 2/3%, (n) | 0 (0) | 21.0 (27) | <0.001 | | Poor histology %, (n) | 0 (0) | 19.4 (25) | <0.001 | | LNM %, (n) | 0 (0) | 13.2 (17) | <0.001 |
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PWDA: pure well-differentiated adenocarcinoma; LNM: lymph node metastasis.
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