Research Article

Diclofenac Sodium Treatment Ameliorates Extrapancreatic Organ Injuries in a Murine Model of Acute Pancreatitis Induced by Caerulein

Table 3

Histopathological results obtained from the stomach tissue according to groups.

Group 1 ()Group 2 ()Group 3 ()Group 4 ()Group 5 ()Group 6 ()Group 7 () value

Congestion0 (0–0.25)1 (1–1.5)a0 (0–1)b1 (0–1)1 (0–1)a1 (1–1.25)a,c1 (0.25–1)a0.008
Edema0 (0–1)1 (1–1.5)a0 (0–1)b0.5 (0–1)1 (0.5–1)1 (1–1.25)a,c,d1 (0.25–1)0.014
Neutropil infiltration0 (0–0.25)1 (1–2)a0 (0–0)b0 (0–0)b0 (0–1)b0 (0–1)b1 (1–1)a,c,d,e,f<0.001
Erosion0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)>0.999
Mononuclear infiltration0.5 (0–1)1 (0.5–1)0.5 (0–1)1 (0–1)1 (0–1.5)1 (1–1)1 (1–1)0.272

Data were shown as median (25th–75th) percentiles, the Kruskal–Wallis test. aThe difference between the considered group and group 1 was found as statistically significant (). bThe difference between the considered group and group 2 was found as statistically significant (). cThe difference between the considered group and group 3 was found as statistically significant (). dThe difference between the considered group and group 4 was found as statistically significant (). eThe difference between the considered group and group 5 was found as statistically significant (). fThe difference between the considered group and group 6 was found as statistically significant ().