Review Article

The Clinical and Steroid-Free Remission of Fecal Microbiota Transplantation to Patients with Ulcerative Colitis: A Meta-Analysis

Table 2

Characteristics of the included studies.

StudyTypeCountrySampleSeverity of the diseaseRouteFresh/frozenPlacebo type

Costello et al. [22]RCTAustralia73Mild-moderate active UCTransplantationFrozenAutologous FMT
Moayyedi et al. [23]RCTCanada75Active UCRetention enemaFresh and frozenConsisting of 50 mL water
Rossen et al. [24]RCTNetherlands48Mild to moderate active UCNasoduodenal tubeFreshAutologous fecal microbiota
Paramsothy et al. [25]RCTAustralia81Active UCInfusionFrozenIsotonic saline adding brown food colourant, odourant, and glycerol cryoprotectant
Ishikawa et al. [26]COHORTJapan36Mild-to-severe active UCColonoscopyFreshAFM monotherapy
Kump et al. 2017 [27]COHORTAustria27Refractory ulcerative colitis, chronic active ulcerative colitisEndoscopyFrozenAntibiotic treatment

Note: RCT: random controlled trials; COHORT: cohort studies; UC: ulcerative colitis; FMT: fecal microbiota transplantation; AFM: amoxicillin, fosfomycin, and metronidazole.