Assessing the Risk Factors for Refractory Eosinophilic Esophagitis in Children and Adults

Table 2

Characteristics of adult population (group B).

Variables	Responder patients (no. 15)	Refractory EoE patients (no. 20)
Age at the diagnosis (mean age)	32.7	39.4
Sex	12 M, 3 F	15 M, 5 F
Number of flare-ups (, % pts)
	Diagnosis’ delay from time of the symptom onset (mean in years)	4.96	5.55
	Follow-up (mean in years)	4.66	3.0
	Symptoms at the onset of EoE		Esophageal
		Esophageal
		Epigastric/abdominal	Epigastric/abdominal
Accidental		Accidental
Endoscopic findings at diagnosis		Exudative/hyperemic	Exudative/hyperemic
		Stenosis/
	Stenosis/
	Food allergy	12 pts	11 pts
PR-		PR-
Tree		Tree
Allergy to inhalants		10 pts	13 pts
		House dust	House dust
		Seasonality of symptoms	6 pts	12 pts
		Pharmacological therapy at diagnosis	10 pts	18 pts
			Fluticasone+	Fluticasone+
	Oral steroids+
	Only
Dietetic therapy	14 pts	10 pts
	Elimination	Elimination
	Oral steroids	8 pts	3 pts
Endoscopic dilatation	0 pt	1 pt
Therapy in case of flare-up		Elimination
		Fluticasone+
Maternal breastfeeding	12 pts	15 pts
Repeated use of antibiotic therapy during infancy	5 pts	14 pts
Tabagic habit	8 pts	9 pts
VAS at the diagnosis (mean)	8.66	7.7
VAS at the follow-up (mean)	2.0	2.7