Research Article
Prognostic Factors Influencing Infectious Complications after Cytoreductive Surgery and HIPEC: Results from a Tertiary Referral Center
Table 2
Postoperative adverse events (as graded by CTCAE severity score v 5.0).
| Adverse events | | % | Grade 1/2 | Grade 3 | Grade 4 | Grade 5 |
| HIPEC-related | 9 | 10.2 | 9 | — | — | — | Renal | 6 | | 6 | — | — | — | Hematological | 3 | | 3 | — | — | — | Infectious complications | 42 | 47.7 | 31 | 7 | 1 | 3 | Sepsis | 2 | | — | — | — | 2 | Abdominal abscess | 8 | | — | 7 | — | 1 | Central line-associated bloodstream infections | 11 | | 11 | — | — | — | Wound infection | 15 | | 15 | — | — | — | Pneumonia | 6 | | 5 | — | 1 | — | Noninfectious complications | 37 | 42.1 | 11 | 11 | 11 | 4 | Acute postoperative pancreatitis | 4 | | — | 3 | 1 | — | Pleural effusion | 10 | | 7 | 3 | — | — | Deep vein thrombosis | 2 | | 2 | — | — | — | Transient ischemic attack | 1 | | — | — | 1 | — | Pulmonary embolism | 2 | | — | — | — | 2 | Respiratory failure | 4 | | 2 | — | 2 | — | Bowel perforation | 4 | | — | — | 3 | 1 | Anastomotic dehiscence | 1 | | — | — | 1 | — | Colostomy necrosis | 1 | | — | — | 1 | — | Urinary fistula | 2 | | — | 2 | — | — | Peritoneal bleeding | 2 | | — | 2 | — | — | Gastric bleeding | 1 | | — | 1 | — | — | Acute myocardial infarction | 3 | | — | — | 2 | 1 | Total | 88 | | 51 (57.9%) | 18 (20.4%) | 12 (13.6%) | 7 (0.8%) |
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