Research Article

Evaluation of the Eighth Edition of the American Joint Committee on Cancer TNM Staging System for Gastric Cancer: An Analysis of 7371 Patients in the SEER Database

Table 3

Comparison of the performance of various editions of the TNM staging system.

ModelConcordance indexROC curveAIC
C-index95% CIAUC95% CI

TNM stage (AJCC 7th)0.7250.717-0.7400.7700.759-0.78156,463.140
TNM stage (AJCC 8th)0.7340.720-0.7410.7730.762-0.78356,396.524
Stage III (AJCC 7th)0.5940.581-0.6070.6070.587-0.62631,552.480
Stage III (AJCC 8th)0.6080.599-0.6240.6210.602-0.64031,515.240
Revised TNM system0.7410.730-0.7480.7740.763-0.78456,355.250

ROC curve: receiver operating characteristic curve; AUC: area under curve; 95% CI: 95% confidence interval; AIC: Akaike information criterion.