Research Article

The Value of Pepsinogen in GC Screening: A Systematic Review and Meta-Analysis

Table 3

Subgroup analysis summary.

SubgroupDORI2 value

Date of publicationBefore 20103.9880.10%<0.01
After 20106.2484.00%<0.01

Country/regionEurope8.4494.00%<0.01
Asia5.0582.50%<0.01

Diagnosis methodPathology4.9686.70%<0.01
Barium meal8.5444.90%0.163

Detection methodELISA4.9786.60%<0.01
Others5.5785.20%<0.01

Document qualityGenerally3.7284.50%<0.01
Higher6.9186.00%<0.01