Narrow-Band Imaging Colonoscopy to Assess Mucosal Angiogenesis in Ulcerative Colitis

Figure 2

Endoscopic and histological findings of the mucosa classified as “obscure pattern” under NBI. (a) Under NBI colonoscopy, the brownish intramucosal capillaries were unclearly observed. (b) The histological degree of inflammation was judged to be moderate. (c) Increased microvessels in the lamina propria and submucosa were revealed by CD31 staining in comparison to “clear pattern.” (d) Increased VEGF staining in either endothelial cells or epithelial cells was observed in comparison to “clear pattern.”

(a)

(b)

(c)

(d)