Research Article
DNMT3B Expression Might Contribute to Abnormal Methylation of RASSF1A in Lager Colorectal Adenomatous Polyps
Figure 4
The methylation and expression of RASSF1A, p16, and hMLH1 in CAP and NCM tissues. (a) MS-PCR analysis of methylation of RASSF1A. (b) Rate of DNA methylation in RASSF1A (). (c) Real-time PCR analysis of the ration of RASSF1A mRNA to β-actin mRNA (). (d) MS-PCR analysis of methylation of p16. (e) Rate of DNA methylation in p16. (f) Real-time PCR analysis of the ration of p16 mRNA to β-actin mRNA. (g) MS-PCR analysis of methylation of hMLH1. (h) Rate of DNA methylation in hMLH1. (i) Real-time PCR analysis of the ration of hMLH1 mRNA to β-actin mRNA.
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