Research Article
Risk Factors of Lymph Node Metastasis in Patients with Pancreatic Neuroendocrine Tumors (PNETs)
Table 1
Detailed demographic, clinical, and pathological features of the study cohort.
| | No. of patients
() | Patients with LN metastases
() |
| | Age at diagnosis | years | years | | Sex | | | | Male | 1043 (53.3%) | 401 (53.6%) | | Female | 913 (46.7%) | 347 (46.4%) | | Race | | | | White | 1289 (65.9%) | 510 (68.2%) | | Black | 223 (11.4%) | 94 (12.6%) | | Hispanic | 249 (12.7%) | 85 (11.4%) | | Asian | 168 (8.6%) | 51 (6.8%) | | Other | 27 (1.4%) | 8 (1.1%) | | Marital status | | | | Unmarried | 607 (31.0%) | 233 (31.1%) | | Married | 1251 (64.0%) | 482 (64.4%) | | Unknown | 98 (5.0%) | 33 (4.4%) | | Insurance status | | | | Uninsured | 47 (2.4%) | 17 (2.3%) | | Insured | 1689 (86.3%) | 619 (82.8%) | | Unknown | 220 (11.2%) | 112 (15.0%) | | Tumor location | | | | Head | 632 (32.3%) | 295 (39.4%) | | Body and tail | 1016 (51.9%) | 332 (44.4%) | | Overlapping | 111 (5.7%) | 46 (6.1%) | | Other | 197 (10.1%) | 75 (10.0%) | | Tumor size | | | | <2 cm | 526 (26.9%) | 75 (10.0%) | | 2 cm-4 cm | 708 (36.2%) | 283 (37.8%) | | >4 cm | 718 (36.7%) | 389 (52.0%) | | Unknown | 4 (0.2%) | 1 (0.1%) | | M stage | | | | M0 | 1644 (84.0%) | 521 (69.7%) | | M1 | 301 (15.4%) | 221 (29.5%) | | Mx | 11 (0.6%) | 6 (0.8%) | | Histology gradea | | | | Well differentiated | 1234 (63.1%) | 401 (53.6%) | | Moderately differentiated | 319 (16.3%) | 127 (17.0%) | | Poorly differentiated | 109 (5.6%) | 84 (11.2%) | | Undifferentiated | 24 (1.2%) | 18 (2.4%) | | Unknown | 270 (13.8%) | 118 (15.8%) |
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aHistology grade was based on WHO classification of tumors 4th edition.
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