S100A12 in Digestive Diseases and Health: A Scoping Review

Table 1

Digestive diseases and their association with S100A12.

Digestive disease	Association with S100A12	References
Atrophic gastritis	Elevated in gastritis samples compared to healthy controls	[52, 53]
Gastric cancer	Decreased in GC samples compared to noncancerous samples	[51]
Necrotizing enterocolitis	Elevated in NEC samples with respect to disease progression	[45–50]
Colitis	Elevated in colitis samples compared to healthy controls	[55, 56]
Colon cancer	Elevated serum S100A12 in CC patients vs. healthy controls	[73]
Irritable bowel syndrome	Elevated in flares	[61, 62]
Inflammatory bowel disease	Elevated in active disease	[37, 59–71]
Crohn’s disease	Elevated in Crohn’s samples vs. healthy controls	[57, 58, 63–65]
Gastrointestinal surgical injury	Elevated in injured patients	[33]