Synthesis of Interleukin-10 in Patients with Ulcerative Colitis and Helicobacter pylori Infection

Table 1

Clinical and demographic characteristics of ulcerative colitis patients divided based upon urea breath test result.

Characteristics	13C-urea breath test; Positive (H. pylori+)		13C-urea breath test; Negative (H. pylori-)		value ≤ 0.05
	No. of patients	Frequency (%)	No. of patients; n =20	Frequency (%)
Onset of disease (years-range)	34 (24-52)	—	28 (17-62)	—	0.14
Mean age (years-range)	42 (34-68)	—	39 (23-69)	—	0.33
Disease duration (years-range)	10 (4-18)	—	10 (3-35)	—	0.64
Body mass index (kg/m^2-range)	24.4 (20.8-29.9)	—	23.8 (18.8-29.9)	—	0.50
Gender					0.61
Male	4	34	7	35	—
Female	7	64	13	65	—
Relapse pattern					0.37
Rare (≤1/year)	10	91	14	70
Common (≥2 relapses/year)	1	9	4	20
Continuous activity (persistent symptoms of active UC without remission period)	0	0	2	10
Disease extension					0.19
Extended colitis	8	73	12	50
Left colitis	0	27	1	5
Proctosigmoiditis	3	0	7	35
Endoscopic activity					0.60
Inactive	2	18	5	20
Mild	4	36	9	50
Moderate	5	46	3	15
Severe	—	—	3	15
Histological activity					0.28
Inactive	4	33	4	20
Mild	4	36	10	50
Moderate	2	18	5	25
Severe	1	9	1	5
Therapy with 5-aminosalicylate					0.27
≤2 g	7	63	7	35
>2 g	4	36	13	65
Laboratories
Hemoglobin (g/dL-range)	14.6 (13.5-17.1)	—	13.9 (11.4-17.5)	—	0.10
Hematocrit (%-range)	44.4 (38.4-50.5)	—	42 (34.7-53.4)	—	0.37
Leukocytes (×10^3-range)	6.1 (3.9-9.6)	—	6.7 (4.8-10.6)	—	0.72
Platelets (K/ul-range)	270 (136-369)	—	280 (201-372)	—	0.53
Albumin (g/dl-range)	4.6 (4.20-5.0)	—	4.3 (3.6-4.8)	—	0.15
ESR (range)	2 (0-11)	—	6.5 (2-59)	—	0.39
High sensitivity CPR (range)	0.12 (0.04-0.26)	—	0.23 (0.02-2.13)	—	0.17