Effect of Combined Live Probiotics Alleviating the Gastrointestinal Symptoms of Functional Bowel Disorders
Table 2
Composition of the gut microbiota at the phylum level (median (IQR)).
Items
Probiotics group
Control group
Independent sample -test or Mann–Whitney test
Baseline
Actinobacteria (%)
2.53 (0.94–8.13)
1.77 (0.50–2.54)
,
Bacteroidetes (%)
39.88 (30.36–47.94)
42.46 (31.77–46.15)
,
Firmicutes (%)
51.29 (37.49–55.67)
45.47 (36.21–53.61)
,
Fusobacteria (%)
0.02 (0.01–0.05)
0.03 (0.01–0.06)
,
Proteobacteria (%)
3.18 (2.40–5.47)
4.25 (3.34–6.60)
,
Others (%)
0 (0–0.01)
0 (0–0.03)
,
Firmicutes to Bacteroidetes ratio
,
Actinobacteria to Bacteroidetes ratio
0.07 (0.02–0.22)
0.04 (0.02–0.07)
,
4 weeks after colonoscopy and treatment
Actinobacteria (%)
1.01 (0.50–2.54)a
5.03 (1.55–10.06)b
,
Bacteroidetes (%)
43.80 (34.72–53.34)
35.17 (26.70–41.67)
,
Firmicutes (%)
42.25 (34.96–53.81)
48.28 (39.01–55.21)
,
Fusobacteria (%)
0.02 (0.01–0.08)a
0.01 (0–0.03)b
,
Proteobacteria (%)
4.40 (3.27–6.92)a
4.54 (2.44–6.29)
,
Others (%)
0 (0–0.01)
0.01 (0–0.06)
,
Firmicutes to Bacteroidetes ratio
,
Actinobacteria to Bacteroidetes ratio
0.02 (0.01–0.02)a
0.15 (0.04–0.38)b
,
IQR: interquartile range. aPaired values of one month after colonoscopy vs. baseline in the probiotics group (, Wilcoxon test). bValues of one month after colonoscopy vs. baseline in the control group (, Wilcoxon test).
