Effect of Combined Live Probiotics Alleviating the Gastrointestinal Symptoms of Functional Bowel Disorders
Table 3
Composition of the gut microbiota at the genus level (median (IQR), %).
Items
Probiotics group
Control group
Mann–Whitney test
Baseline
Bifidobacterium
2.59 (0.41–7.51)
0.80 (0.25–2.40)
,
Collinsella
0.29 (0.01–1.04)
0.47 (0.18–1.08)
,
Enterococcus
0.01 (0–0.02)
0.01 (0–0.01)
,
Lachnospiraceae ND3007
0.20 (0.15–0.35)
0.29 (0.11–0.42)
,
Staphylococcus
0 (0–0.003)
0 (0–0.002)
,
Ruminococcus torques group
0.25 (0.13–0.40)
0.15 (0.08–0.35)
,
Blautia
2.57 (1.57–3.90)
1.77 (1.24–2.47)
,
Ruminococcaceae UCG013
0.17 (0.05–0.33)
0.15 (0.02–0.31)
,
Akkermansia
0.01 (0–0.02)
0.02 (0–0.64)
,
Fusicatenibacter
1.78 (1.04-2.96)
1.41 (0.90-2.22)
,
Eubacterium hallii group
0.28 (0.22–0.57)
0.26 (0.21–0.41)
,
Butyricicoccus
0.18 (0.10–0.27)
0.12 (0.05–0.28)
,
4 weeks after colonoscopy and treatment
Bifidobacterium
0.76 (0.30–2.28)a
3.29 (1.14–8.72)b
,
Collinsella
0.13 (0.01–0.44)a
0.89 (0.30–2.18)b
,
Enterococcus
0.03 (0.01–0.12)a
0.01 (0–0.04)b
,
Lachnospiraceae ND3007
0.18 (0.05–0.35)
0.36 (0.22–0.53)
,P=0.047
Staphylococcus
0 (0–0)a
0 (0–0.002)
,
Ruminococcus torques group
0.10 (0.04–0.15)a
0.16 (0.11–0.33)
,
Blautia
1.31 (0.65–1.68)a
2.44 (1.36–4.78)b
,
Ruminococcaceae UCG013
0.08 (0.02–0.13)a
0.16 (0.03–0.54)
,
Akkermansia
0.06 (0.05–0.08)a
0.03 (0.01–0.49)
,
Fusicatenibacter
0.83 (0.48–1.72)a
2.02 (0.78–2.83)b
,P=0.015
Eubacterium hallii group
0.13 (0.05–0.25)a
0.43 (0.33–0.64)b
,
Butyricicoccus
0.08 (0.04–0.16)a
0.18 (0.07–0.29)
,
IQR: interquartile range. aPaired values of one month after colonoscopy vs. baseline in the probiotics group (, Wilcoxon test). bValues of one month after colonoscopy vs. baseline in the control group (, Wilcoxon test).
