Risk Factors for Mortality in Patients with Aortoesophageal Fistula Related to Aortic Lesions
Table 3
Treatments and outcomes of patients with AEF.
Total
Survivors
Nonsurvivors
Treatment for aortic lesions
Aortic repair
2.3% (5/219)
1.9% (2/103)
2.6% (3/116)
1.000
Aortic graft
32.9% (72/219)
49.5% (51/103)
18.1% (21/116)
<0.001
TEVAR
21.5% (47/219)
26.2% (27/103)
17.2% (20/116)
0.138
Aortic graft+TEVAR
8.7% (19/219)
12.6% (13/103)
5.2% (6/116)
0.057
No treatment
34.7% (76/219)
9.7% (10/103)
56.9% (66/116)
<0.001
Treatment for esophageal lesions
Esophageal repair
16.0% (35/219)
19.4% (20/103)
12.9% (15/116)
0.202
Esophagectomy
27.9% (61/219)
45.6% (47/103)
12.1% (14/116)
<0.001
Esophageal stents
10.0% (22/219)
9.7% (10/103)
10.3% (12/116)
1.000
Esophageal combination treatments
5.0% (11/219)
7.8% (8/103)
2.6% (3/116)
0.120
No treatment
41.1% (90/219)
17.5% (18/103)
62.1% (72/116)
<0.001
Combination of therapy
Conservative treatment
26.0% (57/219)
1.9% (2/103)
47.4% (55/116)
<0.001
Aortic repair±esophageal surgery
2.3% (5/219)
1.9% (2/103)
2.6% (3/116)
1.000
TEVAR
11.9% (26/219)
12.6% (13/103)
11.2% (13/116)
0.835
TEVAR+esophageal repair
2.3% (5/219)
2.9% (3/103)
1.7% (2/116)
0.668
TEVAR+esophagectomy
1.8% (4/219)
2.9% (3/103)
0.9% (1/116)
0.344
TEVAR+esophageal stent
4.6% (10/219)
6.8% (7/103)
2.6% (3/116)
0.196
Aortic graft
2.3% (5/219)
1.9% (2/103)
2.6% (3/116)
1.000
Aortic graft+esophageal repair
10.0% (22/219)
12.6% (13/103)
7.8% (9/116)
0.265
Aortic graft+esophagectomy
17.4% (38/219)
30.1% (31/103)
6.0% (7/116)
<0.001
Aortic graft+esophageal stent
0.9% (2/219)
1.0% (1/103)
0.9% (1/116)
1.000
TEVAR+aortic graft±esophageal treatments
8.7% (19/219)
12.6% (13/103)
5.2% (6/116)
0.057
TEVAR/aortic graft+esophageal treatments
3.2% (7/219)
4.9% (5/103)
1.7% (2/116)
0.258
Esophageal repair
1.8% (4/219)
1.0% (1/103)
2.6% (3/116)
0.624
Esophagectomy
3.2% (7/219)
5.8% (6/103)
0.9% (1/116)
0.053
Esophageal stent
3.7% (8/219)
1.0% (1/103)
6.0% (7/116)
0.069
Antibiotics (>4 weeks)
47.8% (65/136)
53.3% (48/90)
37.0% (17/46)
0.102
AEF: aortoesophageal fistula; TEVAR: thoracic endovascular aortic repair. Data are percentages. Numbers of patients with available data are shown in parentheses.