Review Article

Risk Factors for Mortality in Patients with Aortoesophageal Fistula Related to Aortic Lesions

Table 3

Treatments and outcomes of patients with AEF.

Total Survivors Nonsurvivors

Treatment for aortic lesions
 Aortic repair2.3% (5/219)1.9% (2/103)2.6% (3/116)1.000
 Aortic graft32.9% (72/219)49.5% (51/103)18.1% (21/116)<0.001
 TEVAR21.5% (47/219)26.2% (27/103)17.2% (20/116)0.138
 Aortic graft+TEVAR8.7% (19/219)12.6% (13/103)5.2% (6/116)0.057
 No treatment34.7% (76/219)9.7% (10/103)56.9% (66/116)<0.001
Treatment for esophageal lesions
 Esophageal repair16.0% (35/219)19.4% (20/103)12.9% (15/116)0.202
 Esophagectomy27.9% (61/219)45.6% (47/103)12.1% (14/116)<0.001
 Esophageal stents10.0% (22/219)9.7% (10/103)10.3% (12/116)1.000
 Esophageal combination treatments5.0% (11/219)7.8% (8/103)2.6% (3/116)0.120
 No treatment41.1% (90/219)17.5% (18/103)62.1% (72/116)<0.001
Combination of therapy
 Conservative treatment26.0% (57/219)1.9% (2/103)47.4% (55/116)<0.001
 Aortic repair±esophageal surgery2.3% (5/219)1.9% (2/103)2.6% (3/116)1.000
 TEVAR11.9% (26/219)12.6% (13/103)11.2% (13/116)0.835
 TEVAR+esophageal repair2.3% (5/219)2.9% (3/103)1.7% (2/116)0.668
 TEVAR+esophagectomy1.8% (4/219)2.9% (3/103)0.9% (1/116)0.344
 TEVAR+esophageal stent4.6% (10/219)6.8% (7/103)2.6% (3/116)0.196
 Aortic graft2.3% (5/219)1.9% (2/103)2.6% (3/116)1.000
 Aortic graft+esophageal repair10.0% (22/219)12.6% (13/103)7.8% (9/116)0.265
 Aortic graft+esophagectomy17.4% (38/219)30.1% (31/103)6.0% (7/116)<0.001
 Aortic graft+esophageal stent0.9% (2/219)1.0% (1/103)0.9% (1/116)1.000
 TEVAR+aortic graft±esophageal treatments8.7% (19/219)12.6% (13/103)5.2% (6/116)0.057
 TEVAR/aortic graft+esophageal treatments3.2% (7/219)4.9% (5/103)1.7% (2/116)0.258
 Esophageal repair1.8% (4/219)1.0% (1/103)2.6% (3/116)0.624
 Esophagectomy3.2% (7/219)5.8% (6/103)0.9% (1/116)0.053
 Esophageal stent3.7% (8/219)1.0% (1/103)6.0% (7/116)0.069
Antibiotics (>4 weeks)47.8% (65/136)53.3% (48/90)37.0% (17/46)0.102

AEF: aortoesophageal fistula; TEVAR: thoracic endovascular aortic repair.
Data are percentages. Numbers of patients with available data are shown in parentheses.