Research Article
Nomograms Predicting the Occurrence of Sepsis in Patients following Major Hepatobiliary and Pancreatic Surgery
Table 5
Univariate regression analysis of sepsis based on clinical characteristics and inflammation biomarkers in patients following major surgery.
| Variables | OR | |
| IL-1 (pg/ml) | 0.997 (0.963-1.032) | 0.862 | IL-2 (U/ml) | 1.001 (1.000-1.001) | 0.001 | IL-6 (pg/ml) | 1.003 (1.001-1.004) | ≤0.001 | IL-8 (pg/ml) | 1.000 (1.000-1.001) | 0.125 | IL-10 (pg/ml) | 1.005 (1.001-1.009) | 0.016 | TNF-α (pg/ml) | 1.001 (0.994-1.008) | 0.697 | PCT (ng/ml) | 1.134 (1.066-1.205) | ≤0.001 | CRP (mg/dl) | 1.209 (1.125-1.300) | ≤0.001 | NLR | 1.030 (1.002-1.057) | 0.033 | Perioperative blood transfusion (yes vs. no) | 4.091 (2.240-7.474) | ≤0.001 | ASA scores | 1.715 (0.920-3.197) | 0.090 | Diabetes (yes vs. no) | 2.231 (1.198-4.153) | 0.011 | BMI | 1.12 (1.027-1.221) | 0.01 | Age | 1.026 (1.002-1.050) | 0.036 | Gender (male vs. female) | 0.86 (0.483-1.53) | 0.608 | Operative time | 1.003 (1.002-1.005) | ≤0.001 | Intraoperative blood loss | 1.000 (1.000-1.001) | 0.013 | ALT (U/l) | 1.001 (0.999-1.002) | 0.278 | AST (U/l) | 1.001 (1.000-1.002) | 0.17 | Direct bilirubin (μmol/l) | 1.005 (1.002-1.008) | 0.001 |
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ASA: American Society of Anesthesiologists. . |