Research Article

Nomograms Predicting the Occurrence of Sepsis in Patients following Major Hepatobiliary and Pancreatic Surgery

Table 5

Univariate regression analysis of sepsis based on clinical characteristics and inflammation biomarkers in patients following major surgery.

VariablesOR

IL-1 (pg/ml)0.997 (0.963-1.032)0.862
IL-2 (U/ml)1.001 (1.000-1.001)0.001
IL-6 (pg/ml)1.003 (1.001-1.004)≤0.001
IL-8 (pg/ml)1.000 (1.000-1.001)0.125
IL-10 (pg/ml)1.005 (1.001-1.009)0.016
TNF-α (pg/ml)1.001 (0.994-1.008)0.697
PCT (ng/ml)1.134 (1.066-1.205)≤0.001
CRP (mg/dl)1.209 (1.125-1.300)≤0.001
NLR1.030 (1.002-1.057)0.033
Perioperative blood transfusion (yes vs. no)4.091 (2.240-7.474)≤0.001
ASA scores1.715 (0.920-3.197)0.090
Diabetes (yes vs. no)2.231 (1.198-4.153)0.011
BMI1.12 (1.027-1.221)0.01
Age1.026 (1.002-1.050)0.036
Gender (male vs. female)0.86 (0.483-1.53)0.608
Operative time1.003 (1.002-1.005)≤0.001
Intraoperative blood loss1.000 (1.000-1.001)0.013
ALT (U/l)1.001 (0.999-1.002)0.278
AST (U/l)1.001 (1.000-1.002)0.17
Direct bilirubin (μmol/l)1.005 (1.002-1.008)0.001

ASA: American Society of Anesthesiologists. .