Research Article
p53 Immunohistochemistry Patterns Are Surrogate Biomarkers for TP53 Mutations in Gastrointestinal Neuroendocrine Neoplasms
Table 1
Clinicopathological characteristics of 92 GI-NENs.
| Clinicopathological features | NET no. (%) | NEC no. (%) |
| Sex | | | Male | 18 (51.4) | 39 (68.4) | Female | 17 (48.6) | 18 (31.6) | Age at diagnosis | | | Median | 53 | 66 | Mean | 50.9 | 65.0 | Range | 32-72 | 47-86 | Tumor location | | | Esophagus | 1 (2.9) | 6 (10.5) | Stomach | 12 (34.2) | 38 (66.7) | Small intestine | 3 (8.6) | 4 (7.0) | Colorectum | 19 (54.3) | 9 (15.8) | TNM stage | | | I-II | 26 (74.3) | 30 (52.6) | III | 5 (14.3) | 18 (31.6) | IV | 4 (11.4) | 9 (15.8) | Regional/distant metastasis | | | Positive | 5 (14.3) | 38 (66.7) | Negative | 30 (85.7) | 19 (33.3) |
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