Research Article

p53 Immunohistochemistry Patterns Are Surrogate Biomarkers for TP53 Mutations in Gastrointestinal Neuroendocrine Neoplasms

Table 2

Comparison between p53 IHC staining patterns and TP53 mutation status in 92 GI-NEN cases.

IHC staining patternsMutation status value
Wild-typeMutant type

Pattern types
 Pattern A211<0.001
 Pattern B332
 Pattern C341
Binary classification
 Wild-type pattern332<0.001
 Mutant pattern552