Research Article
Neuroendocrine Neoplasms of the Gallbladder: A Clinicopathological Analysis of 13 Patients and a Review of the Literature
Table 2
Pathology of 13 patients with GB-NENs.
| Patient | Site | Morphology | Tumor size | Mitotic index (/10 HPFs) | Neuroendocrine tumor grade | Neuroendocrine neoplasm histologic subtype | Adenocarcinoma component |
| 1 | Body | Infiltrative | 2 | 30 | MiNENs-NEC | Large cell type | Moderately differentiated | 2 | Fundus | Infiltrative | 3.5 | 20 | MiNENs-NEC | Large cell type | Moderately differentiated | 3 | Neck | Infiltrative | 2.5 | 20 | MiNENs-NEC | Small cell type | Well differentiated | 4 | Neck | Protruding | 4 | 50 | MiNENs-NEC | Large cell type | Well differentiated | 5 | Body | Infiltrative | 5.5 | 40 | MiNENs-NEC | Small cell type | Well differentiated | 6 | Fundus | Protruding | 5 | 20 | MiNENs-NEC | Large cell type | Moderately differentiated | 7 | Body | Infiltrative | 2 | 30 | MiNENs-NEC | Small cell type | Well differentiated | 8 | Fundus | Infiltrative | 7 | 10 | MiNENs-NET G2 | Neuroendocrine tumor | Well differentiated | 9 | Neck | Protruding | 3 | 40 | Amphicrine carcinoma | Amphicrine carcinoma | | 10 | Fundus | Protruding | 2 | 30 | NEC | Small cell type | Absent | 11 | Fundus | Protruding | 4 | 40 | NEC | Large cell type | Absent | 12 | Fundus | Protruding | 0.6 | 1 | NET-G1 | Neuroendocrine tumor | Absent | 13 | Fundus | Protruding | 0.6 | 1 | NET-G1 | Neuroendocrine tumor | Absent |
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