Research Article

Prognostic Utility of Prechemoradiotherapy Albumin-to-Alkaline Phosphatase Ratio in Unresectable Locally Advanced Pancreatic Carcinoma Patients

Table 1

Baseline patient and disease characteristics for the entire study group and per low and high albumin-to-alkaline phosphatase ratio subgroups.

CharacteristicsAll patients ()L-AAPR ()H-AAPR () value

Median age (years) (range)59 (29-79)59 (29-79)58 (32-79)0.86
Age group,
<70 years112 (82.4)57 (80.3)55 (84.6)0.41
≥70 years24 (17.6)14 (19.7)10 (15.4)
Gender,
Female27 (19.9)15 (21.1)12 (19.4)0.62
Male109 (80.1)56 (78.9)53 (81.6)
ECOG performance,
073 (53.7)36 (50.7)37 (56.9)0.54
163 (46.3)35 (49.3)28 (43.1)
Tumor location,
Head112 (82.4)58 (81.7)54 (83.1)0.72
Body/tail24 (17.6)13 (18.3)11 (16.9)
N stage,
069 (50.7)28 (39.4)41 (63.1)<0.001
1-267 (49.3)43 (60.6)24 (36.9)
CA 19-9,
≤90 U/mL39 (28.7)13 (18.3)26 (28.8)0.001
>90 U/mL97 (71.3)58 (81.7)39 (60.1)

Abbreviations: AAPR: albumin-to-alkaline phosphatase ratio; L-AAPR: low AAPR (<0.46); H-AAPR: high AAPR (≥0.46); ECOG: Eastern Cooperative Oncology Group; N stage: nodal stage; CA 19-9: cancer antigen 19-9; ALP: alkaline phosphatase.