Prognostic Value of TRPM7 Expression and Factor XIIIa-Expressing Tumor-Associated Macrophages in Gastric Cancer

Table 2

Relationship between prognostic parameters and overall survival according to multiple Cox regression analysis.

Prognostic parameters	Overall survival (multivariate)
	HR (95% CI)	value
Gender (male/female)	1.12 (0.80–1.57)	0.502
Age (<60, ≥60)	1.26 (0.91–1.76)	0.161
Site (proximal/middle/distal/diffuse)	0.95 (0.82–1.11)	0.579
Histological grade (1/2/3)	1.03 (0.78–1.36)	0.797
Lymphovascular invasion (absent/present)	0.98 (0.69–1.41)	0.952
Depth of invasion (pT1/pT2/pT3/pT4)	0.78 (0.58–1.06)	0.120
Lymph node metastasis (absent/1-2/3-6/≥7)	1.19 (0.95–1.50)	0.145
TNM stage (I/II/III/IV)	3.43 (2.47–4.76)	<0.001
CD4^+ TIL density (low/high)	0.45 (0.15–1.30)	0.142
CD8^+ TIL density (low/high)	0.22 (0.12–0.39)	<0.001
Factor XIIIa^+ TAM density (low/high)	1.38 (0.49–3.88)	0.540
TRPM7 expression (low/high)	8.70 (5.20–14.54)	<0.001

HR: hazard ratio; CI: confidence interval.