Research Article

Differentiation of Isolated Small Bowel Crohn’s Disease from Other Small Bowel Ulcerative Diseases: Clinical Features and Double-Balloon Enteroscopy Characteristics

Table 2

Demographic and clinical features of ISBCD and OSBUD patients.

CharacteristicsISBCDOSBUD value
(%) or median/mean (%) or median/mean

Demographics
Age (years, median)37 (26–47)48 (36–60)<0.001
 ≤2020 (14.4)a1 (1.6)b
 21-3035 (25.2)a8 (12.9)b
 31-4031 (22.3)a11 (17.7)a
 40-5024 (17.3)a16 (25.8)a
 51-6018 (12.9)a11 (17.7)a
 ≥6111 (7.9)a15 (24.2)b
Sex (male, (%))96 (69.1)42 (67.7)0.852
Disease duration (months, median)12.0 (2.0-36.0)6.0 (1.8-24.0)0.183
Medication history of NSAIDs for more than two weeks ( (%))3 (2.2)7 (11.3)0.016
BMI (kg/m2, median)20.52 (19.03-22.84)21.30 (19.05-23.59)0.145
Education level0.090
 Illiteracy8 (5.8)0 (0)
 Primary education99 (71.2)51 (82.3)
 Higher education32 (23.0)11 (17.7)
History of tumor in immediate family14 (10.1)10 (16.1)0.221
Smoking39 (28.1)19 (30.6)0.708
Drinking19 (13.7)5 (8.1)0.258
Blood type0.347
 A48 (34.5)16 (25.8)
 B40 (28.8)17 (27.4)
 O37 (26.6)24 (38.7)
 AB14 (10.1)5 (8.1)
History of perianal lesion ( (%))30 (21.6)4 (6.5)0.008
History of appendectomy ( (%))16 (11.5)3 (4.8)0.135
General symptoms ( (%))
 Fever15 (10.8)5 (8.1)0.551
 Weakness13 (9.4)14 (22.6)0.011
 Weight loss47 (33.8)17 (27.4)0.369
Gastrointestinal symptoms ( (%))
 Abdominal pain117 (84.2)32 (51.6)<0.001
 Diarrhea34 (24.5%)6 (9.7)0.015
 Black stool20 (14.4)13 (35.5)0.001
 Nausea and vomiting44 (31.7)14 (22.6)0.190
 Abdominal distention31 (22.3)13 (21.0)0.833
 Bloody stool17 (12.2)5 (8.1)0.382
 Ileus11 (7.9)2 (3.2)0.348
 Mucous stool5 (3.6)1 (1.6)0.753
 Abdominal mass4 (2.9)0 (0)0.422
 Abdominal discomfort3 (2.2)0 (0)0.554
Extra-intestinal manifestations ( (%))
 Oral ulcers44 (31.7)13 (21.0)0.121
 Genital ulcers6 (4.3)4 (6.5)0.770
 Joint pain25 (18.0)10 (16.1)0.749
 Skin lesions11 (7.9)5 (8.1)1.000
 Episcleritis6 (4.3)1 (1.6)0.583

a and b are the subgroups that differed by Bonferroni correction.