Gastroenterology Research and Practice

Recent Advances in Therapeutics for Ulcerative Colitis


Publishing date
01 Jun 2022
Status
Closed
Submission deadline
21 Jan 2022

1B.S. Abdur Rahman Crescent Institute of Science and Technology, Chennai, India

2Qassim University, Buraydah, Saudi Arabia

3Universidade Federal de Alagoas, Alagoas, Brazil

This issue is now closed for submissions.
More articles will be published in the near future.

Recent Advances in Therapeutics for Ulcerative Colitis

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Inflammatory bowel disease (IBD) is subcategorized into two major diseases, ulcerative colitis (UC) and Crohn’s disease (CD). The incidence of UC is rising steadily due to the increased number of people with an unbalanced diet.

It has been reported that UC is associated with an increased level of various inflammatory markers such as myeloperoxidase (MPO), pro-inflammatory cytokines such as Interleukin (IL)-1β, IL-6, IL-17, IL-21, tumor necrosis factor-alpha (TNF-α), as well as the activation of nuclear factor-kappa B (NF-κB), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2). It is also known that untreated chronic inflammation in the colon leads to the development of colitis-associated cancer. Several signaling pathways have been implicated in the transformation of UC to colitis-associated cancer. In addition, oxidative stress plays a vital role in the pathogenesis of UC. Hence, many natural products act as antioxidants and could be used as therapeutics in UC.

In this Special Issue, new treatment options and novel molecules of natural products origin will be discussed in the prevention and treatment of UC. Original research and review articles are welcome.

Potential topics include but are not limited to the following:

  • Herbal extracts as novel therapeutics for ulcerative colitis
  • Flavonoids as therapeutic agents for ulcerative colitis
  • Alkaloids as therapeutic agents for ulcerative colitis
  • Poly-herbal formulations and herbal decoction as therapeutics for ulcerative colitis

Articles

  • Special Issue
  • - Volume 2022
  • - Article ID 9578307
  • - Research Article

The Effect and Related Mechanism of Action of Astragalus Compatible with Curcumin against Colon Cancer Metastasis in Mice

Jiafei Wu | Decai Tang
  • Special Issue
  • - Volume 2022
  • - Article ID 2163931
  • - Research Article

Protective Effects of Curcumin-Regulated Intestinal Epithelial Autophagy on Inflammatory Bowel Disease in Mice

Jianhua Hong
  • Special Issue
  • - Volume 2022
  • - Article ID 3546455
  • - Research Article

Analysis of Hepatic Artery Infusion (HAI) Chemotherapy Using Randomized Trials of Floxuridine (FUDR) for Colon Cancer Patients with Multiple Liver Metastases

Yuanming Li
  • Special Issue
  • - Volume 2022
  • - Article ID 4003491
  • - Research Article

Gut Microbiota Variations between Henoch-Schonlein Purpura and Henoch-Schonlein Purpura Nephritis

Fang Zhou | Qimin Shao | ... | Chunyan Cai
  • Special Issue
  • - Volume 2022
  • - Article ID 7942845
  • - Research Article

Scientific Evidence of Chinese Herbal Medicine (Gegen Qinlian Decoction) in the Treatment of Ulcerative Colitis

Jinke Huang | Jiaqi Zhang | ... | Xudong Tang
  • Special Issue
  • - Volume 2022
  • - Article ID 3967935
  • - Review Article

Quality of Evidence Supporting the Role of Supplement Curcumin for the Treatment of Ulcerative Colitis: An Overview of Systematic Reviews

Hongshuo Shi | Dan Wang | ... | Tiantian Yang
  • Special Issue
  • - Volume 2022
  • - Article ID 9556161
  • - Review Article

Efficacy and Safety of Endoscopic Submucosal Dissection for Dysplasia in Ulcerative Colitis Patients: A Systematic Review and Meta-Analysis

Qi-Shan Zeng | Zhi-Jing Zhao | ... | Hua-Tian Gan
  • Special Issue
  • - Volume 2022
  • - Article ID 7874751
  • - Research Article

Nursing Value Analysis and Risk Assessment of Acute Gastrointestinal Bleeding Using Multiagent Reinforcement Learning Algorithm

Fang Liu | Xiaoli Liu | ... | Hongrong Wang
  • Special Issue
  • - Volume 2021
  • - Article ID 4227668
  • - Research Article

Exploration of the Potential Mechanisms of Wumei Pill for the Treatment of Ulcerative Colitis by Network Pharmacology

Jinke Huang | Yijun Zheng | ... | Xudong Tang
  • Special Issue
  • - Volume 2021
  • - Article ID 7035557
  • - Research Article

Association of Fecal Microbiota with Irritable Bowel Syndrome-Diarrhea and Effect of Traditional Chinese Medicine for Its Management

Fang Yang | Jiaqi Wu | ... | Bai Ye
Gastroenterology Research and Practice
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Article of the Year Award: Outstanding research contributions of 2021, as selected by our Chief Editors. Read the winning articles.