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Multimodality Treatment of Liver Metastases from Colorectal Cancer

Call for Papers

Current management of colorectal liver metastases requires a multidisciplinary and individualized approach. Hepatic resection has been recognized as the only approach that permits long-term survival, and advances in technology have significantly extended the concept of resectability. Proper use of modern chemotherapy and locally ablative modalities might improve the resectability and prognosis in these patients. For patients who are not surgical candidates and/or fail systemic chemotherapy, liver-directed therapies such as hepatic arterial infusion—and more recently radioembolization—are increasingly being used.

The purpose of this special issue is to publish high-quality research papers as well as review articles addressing recent advances in the multimodal treatment of colorectal cancer liver metastases. We invite investigators to submit manuscripts that are not yet published or not currently under review by other peer-reviewed journals.

Potential topics include but are not limited to the following:

  • Diagnosis and preoperative evaluation
  • Advances in surgical management
  • Systemic chemotherapy (in particular neoadjuvant or perioperative strategies)
  • Ablative treatments: efficacy and challenges
  • Locoregional treatments (hepatic arterial infusion, portal vein embolization, and radioembolization)
  • Biomolecular characterization of liver metastases

Authors can submit their manuscripts through the Manuscript Tracking System at

Submission DeadlineFriday, 20 April 2018
Publication DateSeptember 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

Special Issue Editor in Chief

  • Alessandro Passardi, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Italy

Guest Editors