Gastroenterology Research and Practice

Gastrointestinal Cancer Metastasis

Publishing date
03 Aug 2012
Submission deadline
16 Mar 2012

Lead Editor

1Department of Gastroenterology, Shanghai East Hospital, Tongji University, Shanghai 200120, China

2Division of Digestive Surgery, Department of General Surgery, Hospital of Clinicians of Porto Alegre Medical School, Federal University of Rio Grande do Sul, Porto Alegre 90035-903, RS, Brazil

3Department of Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagome, Bunkyo-ku, Tokyo 113-8677, Japan

4Department of Surgery, Lund University Hospital, 221 00 Lund, Sweden

Gastrointestinal Cancer Metastasis


Gastrointestinal cancers are among the most common malignancies and one of leading causes of death from cancer worldwide. Due to the asymptomatic properties of the disease, most patients are diagnosed at an advanced stage when local and distant metastases happen, leading to poor prognosis. Most deaths from cancer occur as a result of metastasis. Metastatic recurrence is the main obstacle to the improvement in treatment efficacy. To date, there has been no effective treatment for this deadly disease. It is well known that early diagnosis of cancer is able to improve the prognosis. Recently, system biologic methods, such as proteomics and metabolomics, have developed rapidly and shown great potentials in identifying the new diagnostic markers and therapeutic targets for cancers. In addition, tumor microenvironment and cancer stem cells correlate with metastasis. Therefore, research on molecular mechanisms underlying cancer metastasis and new diagnostic markers for detecting or predicting metastasis and improved prognosis is of great importance.

We will take particular interest in research articles on metastatic mechanisms or biomarkers for early detection, predicting response to treatment, and improved prognosis. Reviews on cancer metastasis are welcome. Furthermore, manuscripts involved in a combination of proteomics, genomics, and bioinformatics for investigations of cancer metastasis are of great interest. Potential topics include, but are not limited to:

  • Metastasis and proteomics
  • Metastasis and metabolomics
  • Metastasis and microRNAs
  • Metastasis and tumor microenvironment
  • Cytokines, cell adhesion, and metastasis
  • Molecular characteristics of cancer stem cells or circulating tumor cells and metastasis
  • Biomarker and biotherapy of cancer metastasis
  • New markers and surgical therapy of tumor metastasis

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:

Gastroenterology Research and Practice
 Journal metrics
Acceptance rate25%
Submission to final decision63 days
Acceptance to publication29 days
Journal Citation Indicator0.320
Impact Factor2.260

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