Treatment of Chronic Hepatitis C Virus Infection in Dialysis Patients: An Update

Table 1

Treatment with alpha-interferon or pegylated-alpha interferon in dialysis HCV positive patients: results from 3 meta-analyses.

	Meta-analysis 1 (Fabrizi et al. [16])	Meta-analysis 2 (Gordon et al. [17])	Meta-analysis 3 (Alavian and Tabatabaei; [18])
Number of studies	28	25	33
Number of patients	645	459	770
Overall SVR (standard IFN/Peg-INF) %	39/41	41/37	39.1/39.3
Genotype 1(%)	33	Not reported	Not reported
Treatment discontinuation (standard IFN/Peg-IFN/Placebo) %	19/27/ not reported	26/28/22	22.6/29.7/not reported

SVR: sustained virological response; IFN: alpha-interferon; Peg-IFN: pegylated alpha-interferon.