Tumor Necrosis Factor Receptor 1 Expression Is Upregulated in Dendritic Cells in Patients with Chronic HCV Who Respond to Therapy

Figure 5

TNFR1 membrane expression is higher in dendritic cell subset in SVR compared to NR. Whole PBMCs from control HCV−, SVR and NR were stained with PE-labeled CD123, FITC-labeled CD11, Texas Red-labeled CD14, and/or relative isotype controls as previously described in the methods. CD11+, CD123^dim, CD11−, CD123^high, and CD14+, CD11+ cell subsets were identified by 2-color analysis. Significant differences were noted in the expression of TNFR1 in the histogram from selected cell subset from a control HCV− (column a), SVR (column b), and NR (column c).

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