Hepatitis Research and Treatment / 2011 / Article / Tab 3

Research Article

Etiology and Viral Genotype in Patients with End-Stage Liver Diseases admitted to a Hepatology Unit in Colombia

Table 3

Molecular characterization of HBV isolates corresponding to End-stage liver disease cases: Genotype, Subgenotype and precore/core mutants.

CodeDiagnosisGenotypeSubgenotypeMutationHBV serological markers
pre-CBCPHBsAgIgG anti-HBcHBeAg
1858189617621764

UdeA-009CiFF3μPosPosNeg
UdeA-024CiFF1aTGAGPosPosNeg
UdeA-054CiFF3TAαAGPosPosNeg
UdeA-056HCC/Ci*FF3μPosPosNeg
UdeA-083HCC/Ci*FF3CGT*A*PosPosNeg
UdeA-089βHCC/Ci*FF3CGT*A*PosPosNeg

β: both, tissue and serum samples, Ci: cirrhosis, HCC/Ci*: cirrhosis and hepatocellular carcinoma, ∞: based on complete genome analysis, μ: based on S gene sequence analysis, —: no data, α: nonsense mutation, *: double mutant, Pos: positive, Neg: negative. Strains isolated from Colombian patients: UdeA-009, UdeA-024, UdeA-056, UdeA-083, and UdeA-089. Strain isolated from a Venezuelan patient: UdeA-54. 1.

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