Clinical Study

Circulating Cytokines and Histological Liver Damage in Chronic Hepatitis B Infection

Table 1

Comparison of demographic, clinical, and ALT level, histopathology, and liver stiffness characteristics between HBeAg positive and HBeAg negative patients*.

HBeAg positive ( )HBeAg negative ( ) value

Age > 40yrs3/28 (10.7%)21/36 (58.3%)<0.01
Age (yrs) 0.02
Male gender17/28 (60.7%)28/36 (77.8%)0.14
Mean BMI 0.43
Underlying of DM02/36 (5.6%)0.27
ALT > 60 U/L20/28 (71.4%)16/36 (44.4%)0.03
HBV DNA (logIU/mL) <0.01
HBsAg titer (IU/mL) <0.01
Knodell HAI ≥ 417/28 (60.7%)17/36 (47.2%)0.28
Significant fibrosis11/28 (39.3%)21/36 (58.3%)0.13
Liver stiffness (Kpa) 0.09

Plus-minus values are means ± SD for all comparisons.