Two-Year Follow-Up Analysis of Telaprevir-Based Antiviral Triple Therapy for HCV Recurrence in Genotype 1 Infected Liver Graft Recipients as a First Step towards Modern HCV Therapy
Table 1
Patient characteristics at baseline.
Included patient population for TVR/PegIFN/RBV triple therapy ()
Age (years), mean ± SD
51.8 ± 10.5
Gender (male)
7 (58%)
Body mass index (kg/m2), mean ± SD
26.4 ± 5.3
HCV genotype
1a
2 (17%)
1b
10 (83%)
Previous PegIFN/RBV therapy after OLT
Naive
5 (42%)
Nonresponder/relapsers
7 (58%)
Time between OLT and beginning TVR/PegIFN/RBV therapy (months), mean ± SD
63.7 ± 61.4
Fibrosis grade
1
4 (33%)
2
5 (42%)
3
3 (25%)
HCV viral load (log 10 IU/mL), mean ± SD
6.1 ± 0.8
Bilirubin (μmol/L), mean ± SD
23.9 ± 13.7
ALT (μkat/L), mean ± SD
0.99 ± 0.84
Glomerular filtration rate (mL/min/1.73 m2), mean ± SD