Clinical Study
Add-on Pegylated Interferon Alpha-2a Therapy in Chronic Hepatitis B Japanese Patients Treated with Entecavir
Table 4
Predictability of viral response.
| Factors | Sensitivity | Specificity | PPV | NPV | Accuracy |
| ALT (>20 IU/L) | 67% (8/12) | 64% (7/11) | 67% (8/12) | 64% (7/11) | 65% (15/23) | Reduction rate of HBs Ag at week 12 (>25%) | 75% (9/12) | 82% (9/11) | 82% (9/11) | 75% (9/12) | 78% (18/23) | Reduction rate of HBs Ag at week 16 (>30%) | 75% (9/12) | 82% (9/11) | 82% (9/11) | 75% (9/12) | 78% (18/23) |
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PPV, positive predictive value; NPV, negative predictive value; ALT, alanine aminotransferase; HBs Ag, hepatitis B antigen.
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