Table of Contents
Hepatitis Research and Treatment
Volume 2017, Article ID 6174743, 5 pages
Research Article

Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana

1Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana
2School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana
3Laboratory Department, Ho Municipal Hospital, Ghana Health Service, Ho, Volta Region, Ghana
4Faculty of Health and Allied Sciences, Koforidua Technical University, Koforidua, Eastern Region, Ghana
5Laboratory Department, St. Dominic Hospital, Akwatia, Eastern Region, Ghana

Correspondence should be addressed to Sylvester Yao Lokpo; moc.liamg@43oayretsevlys

Received 14 July 2017; Accepted 12 October 2017; Published 6 November 2017

Academic Editor: Man-Fung Yuen

Copyright © 2017 Sylvester Yao Lokpo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Using prospective blood donors as a proxy, this study was aimed at estimating the burden and five-year (2012–2016) trend of viral hepatitis (HBV and HCV) infection among asymptomatic adult population in Ho. Materials and Methods. A retrospective analysis was done on secondary data extracted from the hospital archives comprising 4,180 prospective blood donors from January 2012 to December 2016. Demographic variables included age and sex, as well as place of residence. Screening results of serum infectious markers (HBV and HCV) were obtained. Results. The prevalence of asymptomatic viral hepatitis (HBV and HCV) infection in the general adult population was 6.94% and 1.84%, respectively. Females recorded a higher burden of HBV and HCV (8.3% and 5.0%) compared to their male peers (6.8% and 1.4%). A significant age variation in HBV antigenaemia was seen with HBV seropositivity peaking among the younger population (less than 20 years’ group) at 11.24% and troughed among the older population (above 50 years’ group) at 0.92%. Conclusion. Asymptomatic viral hepatitis among adult population in the Ho Municipality is estimated at the intermediate to high endemicity level. Preventive measures to reduce the burden are urgently needed and should be targeted at the younger generation.