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HPB Surgery
Volume 7, Issue 2, Pages 157-164
http://dx.doi.org/10.1155/1993/38478
Case Report

Massive Necrotizing Pancreatitis in an Immunosuppressed Renal Transplant Recipient (Successful Therapy)

1Department of Urology and Department of Surgery, Medical College of Ohio and The Toledo Hospital, Toledo, Ohio, USA
2Harris McIntosh Tower, 2121 Hughes Drive, Suite 940, Toledo 43606, Ohio, USA

Received 31 August 1992; Accepted 10 September 1992

Copyright © 1993 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Severe pancreatitis may be associated with massive necrosis of the pancreas and/or retroperitoneal adipose tissue. Toxicity results from the dead tissue and secondary infection. A 45 year old patient, while fully immunosuppressed, developed this complication following cadaveric renal transplantation. He survived continued immunosuppression, 16 operative debridements of the retroperitoneum, and maintained a functioning renal transplant.

In view of the previously reported high mortality rates from mild pancreatitis after transplantation, the current experience warrants further evaluation of the open method of treatment.