Table of Contents
HPB Surgery
Volume 11, Issue 4, Pages 217-224

What Causes Cancer Gallbladder?: A Review

1Bio-chemistry and Molecular Biology Laboratory, Centre of Advanced Study in Zoology, Banaras Hindu University, Varanasi 221 005, India
2Division of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, India

Received 10 May 1998; Accepted 23 October 1998

Copyright © 1999 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Gallbladder cancer is a common malignancy of the biliary tract. It is the fifth common malignancy of the gastrointestinal tract in United States [1] and third in Northern India [2]. Despite such high prevalence, there is scanty published literature about this disease in indexed journals. Therefore, this article is intended to provide a brief overview of gallbladder cancer risk factors, based mainly on published evidence from analytical epidemiology and recent research findings of biologists and practising oncologists. Furthermore, an attempt has been made to establish an association between different causative factors and the occurrence of the disease.