|
| Study name | Study characteristics (country of study, year of study) | Number of people included for the review | Number of node-positive cases* | Population characteristics (age in years, -mean, range, gender ratio M/F) | Routine or Selective lympha-denectomy | Microscopic or macroscopic involvement or both | Group of nodes dissected | Chemotherapy | Indications for chemotherapy |
|
| Nakamura et al. [28] | Japan 1978–1990 | 22 | 6 (27.3%) | Not available | Routine | Microscopic | Hepatic pedicle (hepatoduodenal ligament, retropancreatic and celiac axis) | Adjuvant systemic chemotherapy | All |
|
| Yasui et al. [35] | Japan 1983–1994 | 64 | 8 (12.5%) | Not available | Routine | Both | Hepatic pedicle (hepatoduodenal ligament, retropancreatic, hepatic artery) | Not stated | Not stated |
|
| Beckhurts et al. [8] | Germany 1987–1994 | 126 | 35 (27.8%) | Not available | Routine | Both | Hepatoduodenal ligament | Not stated | Not stated |
|
| Kokudo et al. [18] | Japan 1980–1997 | 94 | 7 (7.4%) | Not available | Not stated | — | Hepatic hilum | Adjuvant local or systemic chemotherapy or no chemotherapy | Not stated |
|
| Ambiru et al. [7] | Japan 1984–1997 | 149 | 8 (5.4%) | Not available | Routine | Both | Hepatoduodenal ligament | Adjuvant local chemotherapy or no chemotherapy | Not stated |
|
| Harms et al. [29] | Germany 1987–1998 | 155 | 39 (25.2%) | Not available | Routine | Both | Hepatoduodenal ligament | Adjuvant local or systemic chemotherapy or no chemotherapy | Poor prognostic factors |
|
| Sanchez-Cespedes et al. [37] | USA | 16† | 8 (50%) | Not available | Not stated | Microscopic (molecular analysis) | Perihepatic nodes | Not stated | Not stated |
|
| Jaeck et al. [16, 25] | France 1993–98 | 160 | 17 (10.6%) | 94 Males/66 Females | Routine | Both | Hepatic pedicle (Hepatoduodenal, retropancreatic,
celiac axis, hepatic artery) | Not stated | Not stated |
|
| Laurent et al. [15] | France 1985–2000 | 156 | 23 (14.7%) | 106 males/50 females 64 years (median) 24–86 years (range) | Routine | Microscopic | Hepatic pedicle (hepatoduodenal, hepatic artery) | Adjuvant systemic chemotherapy | Not stated |
|
| Total | | 942 | 151 (16.0%) | | | | | | |
|
